Misidentified and contaminated cell lines contribute significantly to irreproducible science.
Evidence suggests that up to a third of established tumor cell lines being used for research are affected by inter- or intra-species cross-contamination or have been wrongly identified. Despite the varied causes of irreproducibility from factors that are difficult to control, cell line authentication (CLA) is a relatively simple operation that assures that the cells researchers believe they are working with are actually those cells, and that they are
contaminant-free.
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