--- title: Detecting Low Abundant Endogenous Cardiac Steroids from Biological Fluids description: Download the application note, courtesy of Thermo Fisher Scientific image: https://go.labmanager.com/hubfs/LabManager/Downloads/Thermo/Metabolomics%20Brand%20Backgrnd.jpeg --- ![LabManager\_logo\_light](https://go.labmanager.com/hubfs/LabManager_logo_light.svg "LabManager_logo_light") [![LabManager\_logo](https://go.labmanager.com/hubfs/LabManager_logo.svg "LabManager_logo")](http://www.labmanager.com) # Detecting Low Abundant Endogenous Cardiac Steroids from Biological Fluids ![Metabolomics Brand Backgrnd](https://go.labmanager.com/hs-fs/hubfs/LabManager/Downloads/Thermo/Metabolomics%20Brand%20Backgrnd.jpg?width=600&height=270&name=Metabolomics%20Brand%20Backgrnd.jpg "Metabolomics Brand Backgrnd") Endogenous cardiac steroids are specific inhibitors of the sodium pump (Na+/K+-ATPase) and play important biological roles such as regulating cell growth, differentiation, apoptosis, fibrosis, immunity, carbohydrate metabolism, and nervous and mental functions. Detecting endogenous cardiac steroids from biological fluids is challenging because of their low concentration ranges (pg–ng/mL) and lack of authentic standards. **Download this application note to learn how a novel structure-based MSn discovery approach, utilizing the Thermo Scientific™ Orbitrap ID-X™ Tribrid™ mass spectrometer, enables annotation of cardiac steroids and related compounds based on basic steroid sub-structure identification using MS2 and MS3 spectral tree data.** ## Download the Guide ![Thermo Fisher Scientific](https://go.labmanager.com/hs-fs/hubfs/Technology%20Networks/TN%20Email%20Campaigns%20and%20App%20Alerts/Email%20Campaigns/Thermo/18-06-2020/Thermo%20Fisher%20Scientific.jpg?width=350&name=Thermo%20Fisher%20Scientific.jpg)   Lab Manager needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at anytime. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, [check out our privacy policy by clicking here](https://www.labmanager.com/privacy-policy). ![LabManager\_logo](https://go.labmanager.com/hubfs/LabManager_logo.svg "LabManager_logo") [![Share on Facebook](https://go.labmanager.com/hubfs/lm_social_facebook-1.svg)](http://www.facebook.com/share.php?u=https%3A%2F%2Fgo.labmanager.com%2Fcardiac-steroids%3Futm_medium%3Dsocial%26utm_source%3Dfacebook) [![Share on LinkedIn](https://go.labmanager.com/hubfs/lm_social_linkedin-1.svg)](http://www.linkedin.com/shareArticle?mini=true&url=https%3A%2F%2Fgo.labmanager.com%2Fcardiac-steroids%3Futm_medium%3Dsocial%26utm_source%3Dlinkedin) [![Share on Twitter](https://go.labmanager.com/hubfs/lm_social_twitter-1.svg)](https://twitter.com/intent/tweet?original_referer=https%3A%2F%2Fgo.labmanager.com%2Fcardiac-steroids%3Futm_medium%3Dsocial%26utm_source%3Dtwitter&url=https%3A%2F%2Fgo.labmanager.com%2Fcardiac-steroids%3Futm_medium%3Dsocial%26utm_source%3Dtwitter&source=tweetbutton&text=Detecting%20Low%20Abundant%20Endogenous%20Cardiac%20Steroids%20from%20Biological%20Fluids) [![Share on Email](https://go.labmanager.com/hs-fs/hubfs/Images/TN/Landing%20Page%20Template%20Images/Other/email.png?width=24&name=email.png)](mailto:?subject=Check%20out%20https%3A%2F%2Fgo.labmanager.com%2Fcardiac-steroids%3Futm_medium%3Dsocial%26utm_source%3Demail%20&body=Check%20out%20https%3A%2F%2Fgo.labmanager.com%2Fcardiac-steroids%3Futm_medium%3Dsocial%26utm_source%3Demail) - [About Us](https://www.labmanager.com/about-us) - [Contact Us](https://www.labmanager.com/contact-us) - [Advertising](https://www.labmanager.com/advertising) - [Newsletters](https://www.labmanager.com/newsletters) - [Vendor List](https://www.labmanager.com/vendors) Now part of the LabX Media Group: [LabX Media Group](http://www.labxmediagroup.com/?__hstc=181257784.21576f6272bfcba3d16a5fb8fa824a1a.1570722952660.1580743078369.1580751779639.153&__hssc=181257784.4.1580751779639&__hsfp=2239469692) | [Clinical Lab Manager](http://www.clinicallabmanager.com/?__hstc=181257784.21576f6272bfcba3d16a5fb8fa824a1a.1570722952660.1580743078369.1580751779639.153&__hssc=181257784.4.1580751779639&__hsfp=2239469692) *Lab Manager* c/o LabX Media Group 1000 N West Street, Suite 1200, Wilmington, Delaware, USA, 19801  Toll-Free: 888-781-0328 | (705) 528-6888 Email: [privacy@labmanager.com ](mailto:privacy@labmanager.com)   © 2024 Lab Manager. All rights reserved.