Culturing in the 3rd Dimension


Scaffold-based and scaffold-free approaches

In living tissue, cells exist in three-dimensional (3D) environments that foster intricate cell-cell and cell-matrix interactions and complex transport dynamics. Yet in conventional two-dimensional (2D) cell cultures, cells are grown on flat and rigid substrates that often fail to capture the natural 3D environments present in tissue. Learn more about how 3D cell culture has allowed researchers to overcome the limitations of 2D models.

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